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Mutants

It seems these guys find that rust / oxidation to BE .. the BE ALL END
ALL ..

Whoda thunk ..

Study of huge numbers of genetic mutations point to oxidative stress
as underlying cause
Science Centric | 8 September 2009 10:32 GMT

A study that tracked genetic mutations through the human equivalent of
about 5,000 years has demonstrated for the first time that oxidative
DNA damage is a primary cause of the process of mutation – the fuel
for evolution but also a leading cause of ageing, cancer and other
diseases.

The research, just published in Proceedings of the National Academy of
Sciences, also indicated that natural selection is affecting the parts
of the genome that don’t contain genes – supposedly ‘junk’ DNA that
increasingly appears to have important roles in life processes that
are very poorly understood.

The analysis was done by scientists at Oregon State University,
Indiana University, the University of Florida and University of New
Hampshire, in studies supported by the National Institutes of Health.

This research was unusual, scientists say, because the model animal
used for the study, a type of roundworm called C. elegans, was tracked
through 250 generations and in that period of time accumulated 391
genetic mutations through normal life processes. That’s more than 10
times as many mutations as have ever before been tracked in a study
such as this.

Several Nobel Prizes have been awarded based on studies done with this
roundworm, which was the first animal to have its entire genome
sequenced. And despite their vast evolutionary separation as life
forms, this tiny roundworm and humans still share comparable forms of
DNA maintenance.

‘Genetic mutations in animals are actually pretty rare, they don’t
happen very often unless they are induced by something,’ said Dee
Denver, an assistant professor of zoology at OSU and principal
investigator on the study. ‘The value of using this roundworm is that
it reaches reproductive age in about four days, so we can study
changes that happen through hundreds of generations, using advanced
genome sequencing technology.’

Genetic mutations can take various forms, such as a disruption in the
sequence of DNA bases, larger deletions of whole sections of DNA, or
other events. They are a fundamental part of the biological process of
life and the basis of evolution, allowing organisms to change –
sometimes in ways that are good and lead to greater survival value,
sometimes bad and leading to decline or death. But the process is
difficult to study and a real understanding of the driving forces
behind mutation, its frequency, and the types of mutation that happen
most often has been elusive, researchers say.

A primary finding of the new study is that a predominant number of
genetic mutations – most, but not all of them – are linked to guanine,
one of the four basic nucleotides that make up DNA and form the
genetic code of life. Guanine is known to be particularly sensitive to
oxidative damage.

‘Most life on Earth depends in some form on oxygen, which is great at
the production of energy,’ Denver said. ‘But we pay a high price for
our dependence on oxygen, because the process of using it is not 100
percent efficient, and it can result in free oxygen radicals that can
damage proteins, fats and DNA. And this process gets worse with age,
as free radicals accumulate and begin to cause disease.’

This is one of the first studies, Denver said, that is clearly
demonstrating the effects of oxidative damage at a genome-wide scale.

‘The research showed that the majority of all DNA mutations bear the
signature of oxidative stress,’ Denver said. ‘That’s exactly what you
would expect if you believe that oxidative stress is an underlying
cause of ageing and disease.’

Beyond that, however, the study also found that mutation and natural
selection is also operating in the ‘junk DNA’ parts of the roundworm,
which actually comprises about 75 percent of its genome but
traditionally was not thought to play any major role in life and
genetic processes. This suggests that these poorly-understood and
little appreciated parts of the genome may have important biological
roles that are not yet known, Denver said.

Oxidative stress for decades has been suspected as a mechanism for
some of the processes that lead to ageing and disease, and it has been
studied extensively for that reason. This research provides a better
fundamental understanding of the genetic impacts of oxidative stress
and its role in both genetic disease and evolution, researchers say.

Source: Oregon State University

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh

Man Is A Herbivore!
http://tinyurl.com/a3cc3

DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

.
posted by admin in Uncategorized and have Comments (6)

6 Responses to “Mutants”

  1. admin says:

    spamming canuck cocksucker

  2. admin says:

    On Sep 8, 6:56 pm, Bob Officer <boboffic…@127.0.0.7> wrote:

    > Yeah, but did you notice the article he posted directly contradicts
    > Carole’s claim?

    > —
    > Bob Officer
    > Posting the truthhttp://www.skeptics.com.au

    Rusty doesn’t comprehend even 10% of the abstracts he CCP’s
    He sees the word "iron" and we see the results

    "Book ‘em,  Danno"

  3. admin says:

    "It seems these guys find that rust / oxidation to BE .. the BE ALL END
    ALL ..

    Whoda thunk ..

    Study of huge numbers of genetic mutations point to oxidative stress as
    underlying cause"

    Nope, they said nothing even close.  The oxidative stress discussed is a
    product of normal metabolism in every cell of the body every second of
    the day.  The free radicals of oxygen that result when cells use energy
    has nothing to do with iron "rust" as such.

    If one wants to point to one element in common in every case, it is
    oxygen not iron.  This makes oxygen the cause of all disease not iron,
    to extend what is an already dubious idea.

  4. admin says:

    ALL you shteaters and atheists were TOLD to stay off my threads ..

    DOOOOOO it ..

    Study of huge numbers of genetic mutations point to oxidative stress
    as underlying cause
    Science Centric | 8 September 2009 10:32 GMT

    A study that tracked genetic mutations through the human equivalent
    of
    about 5,000 years has demonstrated for the first time that oxidative
    DNA damage is a primary cause of the process of mutation – the fuel
    for evolution but also a leading cause of ageing, cancer and other
    diseases.

    The research, just published in Proceedings of the National Academy
    of
    Sciences, also indicated that natural selection is affecting the
    parts
    of the genome that don’t contain genes – supposedly ‘junk’ DNA that
    increasingly appears to have important roles in life processes that
    are very poorly understood.

    The analysis was done by scientists at Oregon State University,
    Indiana University, the University of Florida and University of New
    Hampshire, in studies supported by the National Institutes of Health.

    This research was unusual, scientists say, because the model animal
    used for the study, a type of roundworm called C. elegans, was
    tracked
    through 250 generations and in that period of time accumulated 391
    genetic mutations through normal life processes. That’s more than 10
    times as many mutations as have ever before been tracked in a study
    such as this.

    Several Nobel Prizes have been awarded based on studies done with
    this
    roundworm, which was the first animal to have its entire genome
    sequenced. And despite their vast evolutionary separation as life
    forms, this tiny roundworm and humans still share comparable forms of
    DNA maintenance.

    ‘Genetic mutations in animals are actually pretty rare, they don’t
    happen very often unless they are induced by something,’ said Dee
    Denver, an assistant professor of zoology at OSU and principal
    investigator on the study. ‘The value of using this roundworm is that
    it reaches reproductive age in about four days, so we can study
    changes that happen through hundreds of generations, using advanced
    genome sequencing technology.’

    Genetic mutations can take various forms, such as a disruption in the
    sequence of DNA bases, larger deletions of whole sections of DNA, or
    other events. They are a fundamental part of the biological process
    of
    life and the basis of evolution, allowing organisms to change –
    sometimes in ways that are good and lead to greater survival value,
    sometimes bad and leading to decline or death. But the process is
    difficult to study and a real understanding of the driving forces
    behind mutation, its frequency, and the types of mutation that happen
    most often has been elusive, researchers say.

    A primary finding of the new study is that a predominant number of
    genetic mutations – most, but not all of them – are linked to
    guanine,
    one of the four basic nucleotides that make up DNA and form the
    genetic code of life. Guanine is known to be particularly sensitive
    to
    oxidative damage.

    ‘Most life on Earth depends in some form on oxygen, which is great at
    the production of energy,’ Denver said. ‘But we pay a high price for
    our dependence on oxygen, because the process of using it is not 100
    percent efficient, and it can result in free oxygen radicals that can
    damage proteins, fats and DNA. And this process gets worse with age,
    as free radicals accumulate and begin to cause disease.’

    This is one of the first studies, Denver said, that is clearly
    demonstrating the effects of oxidative damage at a genome-wide scale.

    ‘The research showed that the majority of all DNA mutations bear the
    signature of oxidative stress,’ Denver said. ‘That’s exactly what you
    would expect if you believe that oxidative stress is an underlying
    cause of ageing and disease.’

    Beyond that, however, the study also found that mutation and natural
    selection is also operating in the ‘junk DNA’ parts of the roundworm,
    which actually comprises about 75 percent of its genome but
    traditionally was not thought to play any major role in life and
    genetic processes. This suggests that these poorly-understood and
    little appreciated parts of the genome may have important biological
    roles that are not yet known, Denver said.

    Oxidative stress for decades has been suspected as a mechanism for
    some of the processes that lead to ageing and disease, and it has
    been
    studied extensively for that reason. This research provides a better
    fundamental understanding of the genetic impacts of oxidative stress
    and its role in both genetic disease and evolution, researchers say.

    Source: Oregon State University

    Who loves ya.
    Tom

    Jesus Was A Vegetarian!
    http://tinyurl.com/2r2nkh

    Man Is A Herbivore!
    http://tinyurl.com/a3cc3

    DEAD PEOPLE WALKING
    http://tinyurl.com/zk9fk

  5. admin says:

    Spamming Canuck Fuckwit

  6. admin says:

    Useless lmpdck atheist dweeeeeeeb BTCH ..

    Study of huge numbers of genetic mutations point to oxidative stress
    as underlying cause
    Science Centric | 8 September 2009 10:32 GMT

    A study that tracked genetic mutations through the human equivalent
    of
    about 5,000 years has demonstrated for the first time that oxidative
    DNA damage is a primary cause of the process of mutation – the fuel
    for evolution but also a leading cause of ageing, cancer and other
    diseases.

    The research, just published in Proceedings of the National Academy
    of
    Sciences, also indicated that natural selection is affecting the
    parts
    of the genome that don’t contain genes – supposedly ‘junk’ DNA that
    increasingly appears to have important roles in life processes that
    are very poorly understood.

    The analysis was done by scientists at Oregon State University,
    Indiana University, the University of Florida and University of New
    Hampshire, in studies supported by the National Institutes of Health.

    This research was unusual, scientists say, because the model animal
    used for the study, a type of roundworm called C. elegans, was
    tracked
    through 250 generations and in that period of time accumulated 391
    genetic mutations through normal life processes. That’s more than 10
    times as many mutations as have ever before been tracked in a study
    such as this.

    Several Nobel Prizes have been awarded based on studies done with
    this
    roundworm, which was the first animal to have its entire genome
    sequenced. And despite their vast evolutionary separation as life
    forms, this tiny roundworm and humans still share comparable forms of
    DNA maintenance.

    ‘Genetic mutations in animals are actually pretty rare, they don’t
    happen very often unless they are induced by something,’ said Dee
    Denver, an assistant professor of zoology at OSU and principal
    investigator on the study. ‘The value of using this roundworm is that
    it reaches reproductive age in about four days, so we can study
    changes that happen through hundreds of generations, using advanced
    genome sequencing technology.’

    Genetic mutations can take various forms, such as a disruption in the
    sequence of DNA bases, larger deletions of whole sections of DNA, or
    other events. They are a fundamental part of the biological process
    of
    life and the basis of evolution, allowing organisms to change –
    sometimes in ways that are good and lead to greater survival value,
    sometimes bad and leading to decline or death. But the process is
    difficult to study and a real understanding of the driving forces
    behind mutation, its frequency, and the types of mutation that happen
    most often has been elusive, researchers say.

    A primary finding of the new study is that a predominant number of
    genetic mutations – most, but not all of them – are linked to
    guanine,
    one of the four basic nucleotides that make up DNA and form the
    genetic code of life. Guanine is known to be particularly sensitive
    to
    oxidative damage.

    ‘Most life on Earth depends in some form on oxygen, which is great at
    the production of energy,’ Denver said. ‘But we pay a high price for
    our dependence on oxygen, because the process of using it is not 100
    percent efficient, and it can result in free oxygen radicals that can
    damage proteins, fats and DNA. And this process gets worse with age,
    as free radicals accumulate and begin to cause disease.’

    This is one of the first studies, Denver said, that is clearly
    demonstrating the effects of oxidative damage at a genome-wide scale.

    ‘The research showed that the majority of all DNA mutations bear the
    signature of oxidative stress,’ Denver said. ‘That’s exactly what you
    would expect if you believe that oxidative stress is an underlying
    cause of ageing and disease.’

    Beyond that, however, the study also found that mutation and natural
    selection is also operating in the ‘junk DNA’ parts of the roundworm,
    which actually comprises about 75 percent of its genome but
    traditionally was not thought to play any major role in life and
    genetic processes. This suggests that these poorly-understood and
    little appreciated parts of the genome may have important biological
    roles that are not yet known, Denver said.

    Oxidative stress for decades has been suspected as a mechanism for
    some of the processes that lead to ageing and disease, and it has
    been
    studied extensively for that reason. This research provides a better
    fundamental understanding of the genetic impacts of oxidative stress
    and its role in both genetic disease and evolution, researchers say.

    Source: Oregon State University

    Who loves ya.
    Tom

    Jesus Was A Vegetarian!
    http://tinyurl.com/2r2nkh

    Man Is A Herbivore!
    http://tinyurl.com/a3cc3

    DEAD PEOPLE WALKING
    http://tinyurl.com/zk9fk